One of the characteristics shared by mycoses and mycotoxicoses is that neither category of illness is generally communicable from person to person. Mycotoxicoses, in contrast, are more common in underdeveloped nations. Mycoses caused by opportunistic pathogens are largely diseases of the developed world, usually occurring in patients whose immune systems have been compromised by advanced medical treatment. Although the total number affected is believed to be smaller than the number afflicted with bacterial, protozoan, and viral infections, fungal diseases are nevertheless a serious international health problem. The number of people affected by mycoses and mycotoxicoses is unknown. In turn, mycotoxicoses can heighten vulnerability to microbial diseases, worsen the effects of malnutrition, and interact synergistically with other toxins. Thus, the severity of mycotoxin poisoning can be compounded by factors such as vitamin deficiency, caloric deprivation, alcohol abuse, and infectious disease status. The symptoms of a mycotoxicosis depend on the type of mycotoxin the amount and duration of the exposure the age, health, and sex of the exposed individual and many poorly understood synergistic effects involving genetics, dietary status, and interactions with other toxic insults. In contrast to mycoses, mycotoxicoses are examples of “poisoning by natural means” and thus are analogous to the pathologies caused by exposure to pesticides or heavy metal residues. For many mycoses, the ordinary portal of entry is through the pulmonary tract, but direct inoculation through skin contact is not uncommon. Some infections remain localized, while others progress to systemic infection. The mechanisms of pathogenesis of both primary and opportunistic fungi are complex, and medical mycologists have devoted considerable research energy trying to identify the factors that distinguish fungal pathogens from saprophytic and commensal species ( 31, 66). The majority of human mycoses are caused by opportunistic fungi ( 149, 172, 245, 265). Opportunistic pathogens produce illness by taking advantage of debilitated or immunocompromised hosts. Primary pathogens affect otherwise healthy individuals with normal immune systems. The fungi that cause mycoses can be divided into two categories, primary pathogens (e.g., Coccidioides immitis and Histoplasma capsulatum) and opportunistic pathogens (e.g., Aspergillus fumigatus and Candida albicans). Mycoses range from merely annoying (e.g., athlete's foot) to life-threatening (e.g., invasive aspergillosis). Frank growth of fungi on animal hosts produces the diseases collectively called mycoses, while dietary, respiratory, dermal, and other exposures to toxic fungal metabolites produce the diseases collectively called mycotoxicoses. Directions: West on Main, right on Cleveland, two blocks on your right.Fungi are major plant and insect pathogens, but they are not nearly as important as agents of disease in vertebrates, i.e., the number of medically important fungi is relatively low.Calculated Total Monthly Association Fees: 0. Garage Description: RV Possible, Garage Facing Front, Uncovered Parking Spaces 2+.Driveway: Gated, Sidewalk/Curb/Gutter, Paved Driveway.Lot Description: Curb(s)/Gutter(s), Landscape Back, Landscape Front.Living Room Features: Open Beam Ceiling.Kitchen Features: Breakfast Room, Pantry Closet, Quartz Counter.Dining Room Description: Breakfast Nook, Formal Room, Space in Kitchen.Bathroom 1 Features: Low-Flow Toilet(s), Tub w/Shower Over, Window.Primary Bathroom Features: Shower Stall(s), Double Sinks.Cooling Features: Ceiling Fan(s), Central, MultiZone.Equipment: Free Standing Gas Range, Dishwasher, Disposal, Plumbed For Ice Maker.Interior Amenities: Main Level : Bedroom(s), Living Room, Dining Room, Family Room, Full Bath(s), Kitchen, Upper Level : Loft, Master Bedroom, Full Bath(s), Retreat.
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